Deep Brain Stimulation of the Anterior Nucleus of the Thalamus in Intractable Epilepsy

University Hospital, Montpellier10 enrolled

Overview

Deep Brain Stimulation (DBS) of the anterior nucleus of the thalamus (ANT) has been proposed in patients with severe intractable epilepsy. When used, the transventricular approach increases the risk of bleeding due the anatomy around the entry point in the thalamus. To avoid such a complication, the investigators used a transventricular microendoscopic technique.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Refractory Epilepsy

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion criteria: * adult patients * treated between 2010 and 2019 for refractory epilepsy by DBS of the anterior nucleus os the thalamus using microendoscopy * minimum follow-up of 1-year * refractory epilepsy defined as failure of at least 3 antiepileptic drugs Exclusion criteria: \- age \< 18 years

Locations (1)

Uhmontpellier

Montpellier, France

RECRUITING

Outcomes

Primary Outcomes

Absence of hemorraghic complication

Absence of hemorraghic complication on post operative MRI

Time frame: 1 day

Secondary Outcomes

responder rate

50%-responder rate (on seizures)

Time frame: 1 year

responder rate

50%-responder rate (on seizures)

Time frame: 2 years

responder rate

50%-responder rate (on seizures)

Time frame: 5 years

Central Contacts

Gaëtan Poulen, MD

CONTACT

467337262 g-poulen@chu-montpellier.fr

Data from ClinicalTrials.gov

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