In this study, the aerosols emitted during various respiratory activities will be quantified in healthy subjects. The differences in aerosol size spectrum and number during tidal breathing, speaking, coughing and singing will be assessed. Subjects with an endogenously high aerosol emission will repeat the respiratory activities wearing face masks with varying particle filter capacity to investigate the aerosol emission reduction.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
30
Fabric mask, no medical device
Medical face mask (personal protective equipment), CE-certified
Filtering Face Piece with no less than 94% filtering capacity, CE-certified
Fraunhofer ITEM
Hanover, Lower Saxony, Germany
To compare the emitted small particle fraction between various respiratory activities.
Change of particle number per time unit between tidal breathing and various respiratory activities.
Time frame: Day 1, Day 2 to 14
To assess the influence of different face masks on the emitted small particle fraction of various respiratory activities.
Change of particle number per time unit between tidal breathing and selected respiratory activities for community masks, surgical masks, FFP2 and FFP3 respirators in high-emitting subjects.
Time frame: After completion of Study part A (approximately 3 months)
To assess the emitted particle size distribution of various respiratory activities.
Compare changes of emitted particle size spectrum as quantity per size range during tidal breathing and selected respiratory activities.
Time frame: Day 1, Day 2 to 14
To assess the reproducibility of exhaled particle quantification.
Compare results for particle number per time unit and particle size spectrum from visit 1 and 2.
Time frame: Day 2 to 14
To assess the influence of different face masks on the emitted particle size distribution of various respiratory activities.
Compare changes of emitted particle size spectrum as quantity per size range during tidal breathing and selected respiratory activities for community masks, surgical masks, FFP2 and FFP3 respirators in high-emitting subjects.
Time frame: After completion of Study part A (approximately 3 months)
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Filtering Face Piece with no less than 99% filtering capacity, CE-certified