Effect of Amnion Membrane With and Without Taurine on GCF TNF α Level.

Maharishi Markendeswar University (Deemed to be University)45 enrolled

Overview

45 sites in 15 patients with periodontal pockets ≥ 5mm were selected. These selected sites were divided into 3 groups as Group A, B and C.

Group A (Control): 15 sites received only SRP, Group B: 15 sites received SRP with subgingival placement of amnion membrane, Group C: 15 sites received SRP with subgingival placement of Amnion membrane hydrated with Taurine.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Periodontitis

Interventions

Scaling and root planingPROCEDURE

15 sites with periodontal pockets ≥ 5mm received only SRP

Amnion membraneBIOLOGICAL

15 sites with periodontal pockets ≥ 5mm received SRP along with placement of amnion membrane.

TaurineDRUG

15 sites with periodontal pockets ≥ 5mm received SRP along with placement of amnion membrane hydrated with taurine.

Eligibility

Sex: ALLMin age: 29 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: •Systemically healthy patients with sites showing probing depth (PD) ≥ 5mm, clinical attachment level (CAL) ≥ 4 mm, and vertical bone loss ≥ 3 mm on intraoral periapical radiographs with no history of periodontal therapy or use of antibiotics in the preceding 6 months Exclusion Criteria: * Any systemic disease that could influence the outcome of periodontal therapy. * Smokers, alcoholics \& patients with other adverse habits. * Pregnant or nursing women. * Any known allergy or hypersensitivity to any product used in the study. * Patients on long term systemic therapy (antibiotics, anti-inflammatory and any other).

Locations (1)

Department of Periodontology, M.M. College of Dental Sciences and Research.

Ambāla, Haryana, India