The global pandemic caused by the SARS-CoV-2 virus is confronting the German health system with a novel pathogen. This means that a timely evaluation of all available results is required. In the field of intensive care in particular, there are significant gaps in knowledge, particularly with regard to delirium. In this respect, this study also serves directly to investigate the pathways of delirium outcome in COVID-19 patients.
Study Type
OBSERVATIONAL
Enrollment
2,398
Department of Anesthesiology and Operative Intensive Care Medicine Campus Virchow-Klinikum
Berlin, Germany
Incidence of delirium
Delirium is measured by validated screening scores.
Time frame: 01.01.2020 - 21.02.2022
Risk factors for severe COVID-19
Risk factors are defined according to actual literature e.g. obesity, diabetes or hypertension.
Time frame: 01.01.2020 - 21.02.2022
Patient characteristics
Patient characteristics at hospital admission e.g. score level
Time frame: 01.01.2020 - 21.02.2022
Blood gas analysis
Monitoring of blood gas analysis
Time frame: 01.01.2020-31.07.2020
Enteral nutrition
Monitoring of enteral nutrition
Time frame: 01.01.2020-31.07.2020
Parenteral nutrition
Monitoring of parenteral nutrition
Time frame: 01.01.2020 - 21.02.2022
Serum albumin
Monitoring of serum albumin level
Time frame: 01.01.2020 - 21.02.2022
Total protein
Monitoring of total protein level
Time frame: 01.01.2020 - 21.02.2022
Phosphate
Monitoring of phosphate levels
Time frame: 01.01.2020 - 21.02.2022
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Triglyceride
Monitoring of triglyceride levels
Time frame: 01.01.2020 - 21.02.2022
Caloric intake
Caloric intake is measured by total daily energy supply.
Time frame: 01.01.2020 - 21.02.2022
Respiratory setting
Respiratory factors are measured respiratory setting
Time frame: 01.01.2020 - 21.02.2022
Inflammatory laboratory parameter 1
Monitoring of interleukine level
Time frame: 01.01.2020 - 21.02.2022
Inflammatory laboratory parameter 2
Monitoring of cytokine level
Time frame: 01.01.2020 - 21.02.2022
Inflammatory laboratory parameter 3
Monitoring of big immune status
Time frame: 01.01.2020 - 21.02.2022
Inflammatory laboratory parameter 4
Monitoring of t-cell population
Time frame: 01.01.2020 - 21.02.2022
Toxic-drug factors
Toxic-drug factors are measured by concomitant medication.
Time frame: 01.01.2020 - 21.02.2022
Sociodemographic factors
Sociodemographic factors are measured by Audit, Fagerström, occupation, age, gender, cognitive status.
Time frame: 01.01.2020 - 21.02.2022
Breathing hours
Breathing hours are measured by non-invasive and invasive ventilation.
Time frame: 01.01.2020 - 21.02.2022
Length of intensive care unit stay
Length of intensive care unit stay is measured in days of stay in the intensive care unit.
Time frame: 01.01.2020 - 21.02.2022
Length of hospital stay
Length of hospital stay is measured in days of stay in hospital.
Time frame: 01.01.2020 - 31.07.2022
Adverse events
Adverse Events defined by thromboembolic events, nosocomial infections, septic shock, acute renal failure, heart attack, post-intensive care syndrome and death are recorded until hospital discharge.
Time frame: 01.01.2020 - 21.02.2022
Post Intensive Care Unit Syndrome (PICS)
Post Intensive Care Unit Syndrome (PICS) is measured by a validated battery (composite endpoint).
Time frame: 01.01.2020 - 21.02.2022
In-hospital mortality
Mortality is measured in the hospital
Time frame: 01.01.2020 - 21.02.2022
Mortality
Mortality is measured until 180 days
Time frame: 01.01.2020 - 31.08.2022