Preemptive Analgesia of Gabapentoids in Orthopedic Surgery

King Saud University1,000 enrolled

Overview

To address the preemptive analgesic effect of preoperative gabapentoids versus no gabapentoids in orthopedic surgery

Computer search for all studies used preoperative gabapentoids versus no gabapentoids in orthopedic surgery during the last 10 years (from 2011 - 2020)

Study Type

OBSERVATIONAL

Enrollment

1,000

Conditions

Acute Postoperative Pain

Interventions

gabapentoidsOTHER

Preemptive analgesia

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * RCT, during last 10 years, involving orthopedic surgery Exclusion Criteria: * non randomized trials, unavailable study data

Outcomes

Primary Outcomes

Postoperative pain score on rest

Pain score by VAS on rest

Time frame: every hour for the first 24 hours

Postoperative pain during movement

Pain score by VAS during movements

Time frame: every hour for the first 24 hours

Secondary Outcomes

Worst pain score

Highest pain score

Time frame: during the first 24 hours

Least pain score

Lowest pain score

Time frame: during the first 24 hours

Time spend in severe pain

how many hours the patients complaint of severe pain

Time frame: during the first 24 hours

Patient's satisfaction

Satisfaction by the quality of analgesia

Time frame: during the first 24 hours

Data from ClinicalTrials.gov

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