This study is aimed to explore the effect of physical exercise and nutrition supplement on improving frailty, depressive symptoms, and quality of life in community-dwelling older population.
Objective: This study is aimed to explore the effect of physical exercise and nutrition supplement on improving frailty, depressive symptoms, and quality of life in community-dwelling older population. Methods: We conduct a quasi-experimental study to measure frailty, depressive symptoms, and quality of life before and after intervention. A total of 120 community-living older adults with frailty identified by Fried's phenotype method are assigned to four groups: physical exercise group, nutrition supplements group, physical exercise and nutrition supplements group, and control group. Each participants in the assigned group will receive 12 weeks intervention. Measurements include frailty (Fried's phenotype method), depressive symptoms (Geriatric Depression Scale-15, GDS-15), and quality of life (WHOQOL-BREF). Data analyses include describe statistics, Chi-square test, and Analysis of Variance. A Generalized estimating equations (GEE) will be used to examine the effect of physical exercise and nutrition supplement on improving frailty, depressive symptoms, and quality of life.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
120
The participants in physical exercise group will receiving individual physical exercise lead by physiological therapist for 60 minutes/ three times weekly for 12 weeks.
The participants in nutrition supplements group will receiving Branched-Chain Amino Acids 5 g Branched-Chain Amino Acids every day for 12 weeks.
The participants in physical exercise group will receiving physical exercise lead by physiological therapist for 60 minutes/ three times weekly for 12 weeks and 5 g Branched-Chain Amino Acids every day for 12 weeks.
Taipei Medical University
Taipei, Taiwan
frailty score
Frailty will examined using Fried's phenotype method and higher score indicates more frailty
Time frame: frailty score at baseline
frailty score
Frailty will examined using Fried's phenotype method and higher score indicates more frailty
Time frame: through study completion, an average of 12 weeks
Depressive symptoms score
Depression will measured using Geriatric Depression Scale-15 (GDS-15) and and higher score indicates more depression
Time frame: Depressive symptoms at baseline
Depressive symptoms score
Depression will measured using Geriatric Depression Scale-15.
Time frame: through study completion, an average of 12 weeks
Quality of Life score
Quality of Life will examined using World Health Organization Quality of Life scale and higher score indicate better quality of life
Time frame: Quality of Life at baseline
Quality of Life score
Quality of Life will examined using World Health Organization Quality of Life scale and higher score indicate better quality of life
Time frame: through study completion, an average of 12 weeks
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