Acute upper respiratory tract infection(AURI) is common in children, and viral infection is the main cause. However, several children with viral infection are easy to suffer from secondary bacterial infection, and the mechanism is unclear.
Lactate is an important molecule in the spread and metastasis of tumor by suppressing the innate immune response. As is known, the immune system is not mature in children and it is reverse related to the age of children. An reasonable hypothesis is that the lactate is a independent risk factor in the children with viral infection progress to bacterial infection. Here, our aim is to test the hypothesis.
Study Type
OBSERVATIONAL
Enrollment
400
a child is infected by virus only
a child is infected by virus and progress to bacterial infection
Chen
Chongqing, Chongqing Municipality, China
level of lactate
level of lactate in both viral and viral and bacterial infection groups
Time frame: three days after admission
the level of lactate dehydrogenase(LDH)
level of LDH in both viral and viral and bacterial infection groups
Time frame: three days after admission
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.