Phthalates are a group of ubiquitous synthetic endocrine-disrupting chemicals. Fetal and neonatal periods are particularly susceptible to endocrine disorders, which prenatal exposure to phthalates causes. There is increasing evidence concerning the potential endocrine disrupting for phthalate exposure during pregnancy. Prenatal exposure phthalates would disrupt the level of sex hormone in pregnant women, which results in preeclampsia. The relationship of prenatal phthalate exposure with maternal and neonatal outcomes in human beings was often sex-specific associations. Because of the potentially harmful influence of prenatal phthalate exposure, steps should be taken to prevent or reduce phthalate exposure during pregnancy.
Study Type
OBSERVATIONAL
Enrollment
60
test mothers Phthalates in their urine, and test estrogen and progesterone receptor in placental tissue
department of obstetrics of Second Affiliated Hospital of Wenzhou Medical University
Wenzhou, Zhejiang, China
Phthalates in urine
Collect the urine of pregnant women and test the abundance of Phthalates
Time frame: 37 weeks to 40 weeks gestation
The female progesterone
Collect the placenta tissue of pregnant women and test the abundance of estrogen progesterone receptor
Time frame: 37 weeks to 40 weeks gestation
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