The objective of this pilot study is to assess the safety, functional outcome, feasibility and the potential benefits of synthetic mesh strip and gluteus flap reconstruction in perineum in case-control setting.
Several studies have reported over 30% morbidity with perineal wound healing after abdominoperineal resection. Preoperative radiotherapy seems to be a strong predictor for perineal complications. Musculocutaneus flaps and use of biological mesh seem to minimize perineal morbidity.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
30
Intervention group will be compared to historical patients in a case-control setting. Intervention group will have a mesh enhanced gluteus plasty made to reconstruct perineum after abdominoperineal resection.
Oulu University Hospital
Oulu, Finland
Complications
Comprehensive complication index
Time frame: 30 days
Surgical site infections
Surgical site infections
Time frame: 30 days
Reoperation rate
Reoperation rate
Time frame: 30 days
Operative time
Operative time to reconstruct perineum
Time frame: 30 days
Length of hospital stay
Primary length of stay at the hospital
Time frame: 30 days
Costs of treatment materials
Costs of treatment materials
Time frame: 30 days
Total perineal healing time
Time from operation to complete perineal healing
Time frame: 1 year
Perineal fistula
Perineal sinus or fistula
Time frame: 30 days
Perineal hernia
Perineal hernia incidence
Time frame: 12 months
Gluteus muscle function measured by time stands test
Gluteus muscle function measured by time stands test
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Time frame: 12 months