This online-based, observational retrospective registry aims to (i) study the rate of cardiovascular events, encompassing venous thromboembolic and arterial events, in consecutive hospitalized patients with coronavirus (Covid19), (ii) investigate the prevalent use of thromboprophylaxis, (iii) describe the use of imaging tests for the detection of cardiovascular events in patients with Covid19. This will also facilitate and constitute the basis for the conduction of interventional thromboprophylaxis studies in patients with Covid19.
Study Type
OBSERVATIONAL
Enrollment
2,708
Fatal or non-fatal venous thromboembolism (VTE)
Rate of thromboembolic events encompassing pulmonary embolism (PE) and deep vein thrombosis (DVT)
Time frame: during index hospitalization for Covid19
Fatal or non-fatal cardiovascular events
Rate of cardiovascular events encompassing stroke and myocardial infarction
Time frame: during index hospitalization for Covid19
All-cause death
Rate of death from any cause
Time frame: during index hospitalization for Covid19
Prevalence of cardiovascular risk factors
Baseline prevalence of cardiovascular risk factors and use of specific medications (statins, Angiotensin-converting enzyme \[ACE\] inhibitors)
Time frame: at baseline/enrollment
Length of hospitalization
Duration of inpatient stay
Time frame: first index hospitalization for Covid19
Prevalent use of in-hospital thromboprophylaxis
Use of unfractionated heparin (UFH), low-molecular weight heparin (LMWH), or direct oral anticoagulants (DOAC) on/after admission due to Covid19
Time frame: during index hospitalization for Covid19
In-hospital course of D-dimer (μg/mL)
Course of laboratory biomarker
Time frame: during index hospitalization for Covid19
In-hospital course of Troponin (ng/ml)
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Unicamp (Universidade Estadual de Campinas; University of Campinas)
Campinas, Brazil
Hospital Sírio-Libanês
São Paulo, Brazil
Hospital de Campanha Anhembi
São Paulo, Brazil
Amager and Hvidovre Hospital
Hvidovre, Denmark
Universitätsklinikum Koeln
Cologne, Germany
Augusta-Krankenhaus Duesseldorf
Düsseldorf, Germany
Universitäts-Herzzentrum Freiburg
Freiburg im Breisgau, Germany
Universitätsklinikum des Saarlandes und Medizinische Fakultät der Universität des Saarlandes
Homburg, Germany
DRK Kliniken Berlin Köpenick
Köpenick, Germany
Universitätsmedizin Mainz
Mainz, Germany
...and 20 more locations
Course of laboratory biomarker
Time frame: during index hospitalization for Covid19