Refractive Outcomes After Cataract Surgery in Eyes With Pseudoexfoliation Syndrome

Medical University of Lublin80 enrolled

Overview

To evaluate the refractive outcomes of cataract surgery in PEX syndrome and determine which of the commonly used IOL formulas (SRK/T, Barrett Universal II and Hill-RBF) is the best in predicting postoperative refractive outcomes in PEX.

The primary outcome measure was to compare refractive outcomes (MAE, MedAE, percentage of eyes within certain range of prediction error) in PEX and control eyes. The secondary outcome measure was to determine whether any of IOL power prediction formulas (SRK/T, Barrett Universal II and Hill-RBF) is more precise for these challenging eyes.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Refractive Errors Cataract

Interventions

Phacoemulsification cataract surgeryPROCEDURE

All surgeries were performed using Infinity (Alcon Laboratories, Inc.) under topical anaesthesia by one surgeon through 2.2 mm incision in the upper corneal limbus. The hydroimplantation of IOL to the capsular bag was performed in all cases.

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * senile cataract with/without PEX Exclusion Criteria: * corneal pathology * glaucoma, * corneal astigmatism greater than 2.0 diopters (D), * previous eye surgery or subjects with decreased vision due to other reasons than cataract (e.g., exudative age-related macular degeneration (AMD), proliferative diabetic retinopathy, inflammatory eye diseases), * intraoperative complications, * postoperative corrected distance visual acuity (CDVA) worse than 20/40, * axial length below 21 mm and above 25 mm, * dense cataracts or poor fixation requiring ultrasound biometry * eyes with manifest iridophacodonesis and those in which a capsular tension ring was inserted

Outcomes

Primary Outcomes

To compare refractive outcomes in PEX and control eyes.

To measure MAE, MedAE, percentage of eyes within certain range of prediction error after cataract surgery

Time frame: 3 months

Secondary Outcomes

To determine whether any of IOL power prediction formulas is more precise for these challenging eyes.

To measure the effects of IOL power calculation formulas - SRK/T, Barrett Universal II and Hill-RBF - on postoperative refraction

Time frame: 3 months

Data from ClinicalTrials.gov

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