Bone Health and Microbiome in Persons With Type 1 Diabetes

Inclusion Criteria: \- Willing and able to comply with study protocol For participants with type 1 diabetes (T1D): \- T1D diagnosed clinically by an endocrinologist as documented in medical records. Exclusion Criteria: * use of oral or parenteral antibiotics within 3 months * use of probiotics/prebiotics/synbiotics within 3 months of enrollment; persons who eat yogurt will be asked to stop for 30 days prior to stool collection * use of medications that will affect bone, including glucocorticoids, bisphosphonates * chronic medications (other than insulin for those with T1D or a stable dose of thyroid hormone) * uncontrolled chronic gastrointestinal disease including celiac disease (persons with T1D will be screened for celiac disease with a Tissue Transglutaminase Antibody (tTG)/Immunoglobulin A (IgA) if not done in prior 2 years) * known genetic syndrome that predisposes the participant to fracture (such as osteogenesis imperfect) or skeletal dysplasia that would affect skeletal assessment (such as hypochondroplasia) * pregnancy * Any other condition that in the opinion of the investigator would jeopardize the safety or rights of the subject participating in the study or would make it unlikely the subject could complete the study Additional Exclusion Criteria for Healthy Controls: * Presence of any diabetes autoantibody * Presence of any type of diabetes or hyperglycemia (HbA1c≥5.7%)