Risk Factors for COVID-19 Mortality

Teodoro Marcianò200 enrolled

Overview

COVID-19 pandemic has deeply burdened hospitals all over the world. A two-stage disease has been hypothesized due to quick worsening of clinical status after 7-10 days from the beginning of first symptoms, generally flu-like symptoms. Predicting clinical worsening could help to address major efforts towards higher risk patients. During the last year most observational studies, generally retrospective, has been conducted, identifying some risk factors such as age, obesity, male gender, cardiovascular disease, COPD, diabetes etc. The study goal is to collect systematically a variegate amount of clinical, biometric, laboratory and radiological data from patients admitted to the Emergency Medicine Ward of Piacenza Hospital (Italy), in order to prospectively analyze what characteristics are associated to higher risk of mortality.

Study Type

OBSERVATIONAL

Enrollment

200

Conditions

COVID-19 Virus Infection Population at Risk Acute Respiratory Distress Syndrome

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Admission to the Emergency Medicine Ward from the Emergency Department of Piacenza Hospital (Italy) * Confirmed COVID-19 diagnosis through molecular test obtained from nasal-pharyngeal swabs in the Emergency Department * Age above 18 Exclusion Criteria: * inability to obtain an informed consent due to neurological conditions. * patient's refusal to sign the informed consent * inability of researchers to recruit the patient in the first 24 hours from the admission.

Outcomes

Primary Outcomes

Mortality rate

Number of patients who die for any cause in the first 28 days after admission

Time frame: 28 days after admission

Secondary Outcomes

Need of invasive ventilation

Number of patients who need invasive ventilation in the first 15 days after admission

Time frame: 15 days after admission