Occupational Hand Eczema - Testing of a Prevention-concept

National Allergy Research Center, Denmark50 enrolled

Overview

Randomised controlled trial examining the effect of decreased waiting time for the first doctors' appointment, patient education, glove counselling and counselling at departments of social or occupational medicine on severity of hand eczema, quality of life, use of corticosteroids, and jobsituation 3-12 months after intervention in patients with suspected occupational contact dermatitis of the hands.

Patients with suspected occupational hand eczema are recruited to the study on basis of their referral from general practitioner to dermatologist. Patients are randomised to either control or intervention group. The control group is treated and followed-up by the dermatologist they have been referred to, while the intervention group is treated and followed-up at Gentofte Hospital skin department with a maximum waiting time of 3 weeks. At the skin department at Gentofte Hospital, the patients in the intervention group receive patient education in prevention and treatment of hand eczema, glove counselling, personal product screening by a chemistry engineer, extended allergy testing and the standard treatment of hand eczema. Patients in both the control and intervention group are asked to fill out a questionnaire at 3, 6, 9 and 12 months after inclusion in the study. The questionnaire contains questions about quality of life, severity of hand exzema, jobsituation, use of healthcare service and use of medicine. Furthermore, prescriptions of medicine are registered in both control and intervention group at 3, 6, 9 and 12 months.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

NONE

Enrollment

Conditions

Occupational Contact Dermatitis

Interventions

Treatment at the skin department at Gentofte HospitalOTHER

Treatment in a hospital setting at Gentofte Hospital skin department

Eligibility

Sex: ALLMin age: 15 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Referred from a general practitioner to a dermatologist * Hand eczema within the last 3 months * Suspicion that the hand eczema is work-related (either patient and/or doctors suspicion) Exclusion Criteria: * Does not read and write danish * Severe psychiatric illness * Pregnancy

Locations (1)

Gentofte Hospital, Skin department

Hellerup, Denmark

Outcomes

Primary Outcomes

Change in severity of handeczema assessed by the hand eczema severity index (HECSI) 0-360 points (0 best, 360 worst)

The hand eczema severity index (HECSI)

Time frame: Change between baseline and 3 months

Change in severity of handeczema assessed by the photographic guide for severity of handeczema

Self-assessed photographic guide

Time frame: Change between baseline and 3 months

Change in severity of handeczema assessed by the photographic guide for severity of handeczema

Self-assessed photographic guide

Time frame: Change between baseline and 6 months

Change in severity of handeczema assessed by the photographic guide for severity of handeczema

Self-assessed photographic guide

Time frame: Change between baseline and 9 months

Change in severity of handeczema assessed by the photographic guide for severity of handeczema

Self-assessed photographic guide

Time frame: Change between baseline and 12 months

Change in severity of handeczema assessed by a visual analog score 0-100 (0 best, 100 worst)

Visual analog Score for severity of handeczema

Time frame: Change between baseline and 3 months

Change in severity of handeczema assessed by a visual analog score 0-100 (0 best, 100 worst)

Visual analog Score for severity of handeczema

Time frame: Change between baseline and 6 months

Change in severity of handeczema assessed by a visual analog score 0-100 (0 best, 100 worst)

Data from ClinicalTrials.gov

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Visual analog Score for severity of handeczema

Time frame: Change between baseline and 9 months

Change in severity of handeczema assessed by a visual analog score 0-100 (0 best, 100 worst)

Visual analog Score for severity of handeczema

Time frame: Change between baseline and 12 months

Amount of corticosteroids prescribed within the last year

Amount of corticosteroids prescribed wihtin the last year

Time frame: Baseline

Amount of corticosteroids prescribed within the last 3 months

Time frame: 3 months

Amount of corticosteroids prescribed within the last 3 months

Time frame: 6 months

Amount of corticosteroids prescribed within the last 3 months

Time frame: 9 months

Amount of corticosteroids prescribed within the last 3 months

Time frame: 12 months