3D FLAIR Versus Coronal T2-WI MRI in Detecting Optic Neuritis (FLACON)

Fondation Ophtalmologique Adolphe de Rothschild1,200 enrolled

Overview

3D FLAIR, 3D T1 FAT SAT, coronal T2 and coronal T1 dixon sequences were usually used to assess visual deficits in MRI. Optic nerve examination is preferably performed using a coronal T2 sequence in order to detect a hypersignal suggestive of inflammation whereas brain examination is preferably performed using a 3D FLAIR sequence to highlight signs of spatial dissemination and lesions suggestive of multiple slerosis (MS). Recently, a study based on a small number of patients showed the interest of 3D FLAIR in the detection of the hypersignal of the optic nerve.The objective of this retrospective study is to determine whether a single 3D FLAIR sequence allows simultaneous exploration of the optic nerve and the brain for the positive diagnosis of optic neuropathy and/or MS.

Study Type

OBSERVATIONAL

Enrollment

1,200

Conditions

Optic Neuritis Multiple Sclerosis Encephalopathy

Interventions

Magnetic Resonance Imaging

Comparing 3D FLAIR versus Coronal T2-WI MRI in detecting Optic Neuritis

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age \> 18 years * Decrease in visual acuity explored in MRI between january 2018 and january 2020 Exclusion Criteria: * Past history of episode of Optic neuritis

Locations (1)

Hôpital Fondation Adolphe de Rothschild

Paris, Île-de-France Region, France

Outcomes

Primary Outcomes

Detection of optic neuropathies using MRI

MRI comparison of the diagnostic performance of the 3D FLAIR sequence and the T2 coronal in the detection of optic neuropathies.

Time frame: 1 hour

Data from ClinicalTrials.gov

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