This is a 5-year cross-disciplinary sexually transmitted infection (STI) project involving a) territory-wide and community-based studies (survey and specimen collection); b) simulation of STI transmission dynamics and comparison of STI intervention strategies through mathematical modelling and cost-effectiveness analysis. The aim of this project is to assess the burden and the transmission dynamics of STIs in the general population and men who have sex with men (MSM) in Hong Kong. Around 1300 sexually experienced adults and 900 MSM would be recruited, 100 participants would be invited for individual in-depth interviews. Main outcome measures include STI history and service preference, effectiveness as measured by the proportion of new STI infections (chlamydia, gonorrhoea and human papillomavirus infections) averted above base-case scenario, and incremental cost-effectiveness ratio.
After completion of baseline questionnaire, the participants are invitied for STI self-sampling. If agree, a package of self-sampling kits, instructions, and packaging materials for return post would be delivered to their selected collection points. The second round of self-sampling would be offered at least one year from the first round of self-sampled specimens collected.
Study Type
OBSERVATIONAL
Enrollment
1,977
participants in both groups will receive self-sampling kits and deliver the collected samples to laboratory for testing
The Chinese University of Hong Kong
Hong Kong, Hong Kong, China, Hong Kong
self-reported STI diagnosis in questionnaire
number of STI diagnosis
Time frame: up to 2 years
effectiveness of STI intervention strategies
incremental cost-effectiveness ratio
Time frame: 10 years
STI symptom reported in questionnaire
types of symptom presentations
Time frame: 12 months
willingness to pay for STI testing reported in questionnaire
willingness to pay (HKD)
Time frame: 12 months
prevalence of STI estimated through laboratory testing
prevalence of chlamydia trachomatis, Neisseria gonorrhoeae and human papillomavirus infections from self-collected samples
Time frame: 12 months
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