The effect of continuous blood purification (CBP) in children is unclear. Also, the timing of early application is still being explored. In this study, we need to explore the efficacy and the timing of application of CBP in children with sepsis or septic shock.
Early intervention of CBP can remove inflammatory factors in patients with sepsis and reduce the damage of inflammatory factors to organs; at the same time, it can also promote the body's immune response, significantly improve immune dysfunction, and restore the body's immune balance. However, the timing of early application of CBP in childhood sepsis is still unclear. Therefore, it is necessary to further explore the treatment and prognosis of this technology in the early treatment of sepsis.
Study Type
OBSERVATIONAL
Enrollment
90
continuous blood purification can prevent or treat fluid overload in children with septic shock or other sepsis-associated organ dysfunction who are unresponsive to fluid restriction and diuretic therapy management of septic AKI patients, particularly those with hemodynamic instability or fluid overload. Also, it can remove cytokines
Children'S Hospital of Fudan University
Shanghai, Shanghai Municipality, China
RECRUITINGsurvival rate
The survival rate of children in 28 days after hospital discharge
Time frame: 28 days after hospital discharge
The creatinine level of non-survival children with sepsis
The creatinine level of non-survival children with sepsis in 28 days after hospital discharge
Time frame: 28 days after hospital discharge
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