Infants with congenital heart disease (CHD) are usually born with a normal weight but develop malnutrition over time, and about 20-50% of these children are usually malnourished. Malnutrition in these patients is multifactorial. To compensate for the increased need for infants and children with CHD, an increase in their caloric intake has been suggested. However, these patients may not be able to receive enough to meet the increased needs and catch-up growth. One of the suggested solutions in these patients to compensate for inadequate food intake is to increase the caloric density of milk or formula. For this purpose, the use of special formulas with higher calorie density or enrichment of normal formula or breast milk using special enrichment formula could be suggested. In the present study, the effect of increasing calorie intake by increasing the concentration of normal formula in comparison with formula with standard concentration on weight gain and other anthropometric indices of CHD patients with malnutrition will be compared.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
65
Regular infant formula will be concentrated to give a calorie density of about 90 kcal/100 mL.
Rajaei Cardiovascular, Medical & Research Center
Tehran, Iran
Weight
Body weight of infant or child
Time frame: Change from baseline at 2 months
Length
Recumbent length of infant or child
Time frame: Change from baseline at 2 months
Mid-arm circumference
mid upper-arm circumference of infant or child
Time frame: Change from baseline at 2 months
Head circumference
Head circumference
Time frame: Change from baseline at 2 months
IGF1
Serum IGF1
Time frame: Change from baseline at 2 months
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