Necrotizing enterocolitis(NEC) is one of the most serious disease in the newborn infants, and two and more grades of NEC usually lead to surgery, even death. But, it is difficult to predict when to operate the surgery.
Necrotizing enterocolitis(NEC) is characterized by vomit, abdominal distention, hypoactive bowel sounds and bloody stools, even shock, disseminated intravascular coagulation(DIC) and sepsis. X-ray is shown Intestinal wall gas and/or portal vein pneumatosis and pneumoperitoneum. Two and more grades of NEC in newborn infant is a urgent condition, and whether or not operation is difficult to predict. Here, the investigators develop a score system including five parameters(abdominal circumference, base excess, heart rate, severities of respiratory distress, sepsis) in one retrospective cohort, and the score system is used and assessed to predict the need for surgery in another prospective cohort.
Study Type
OBSERVATIONAL
Enrollment
800
two and more grades of NEC is assessed using the score system to predict the need for surgery
two and more grades of NEC is assessed using the usual method to predict the need for surgery
Chen（陈）
Chongqing, Chongqing Municipality, China
RECRUITINGsensitivity of the score system for predicting the need of surgery
sensitivity of the score system for predicting the need of surgery is assessed
Time frame: before surgery
specificity of the score system for predicting the need of surgery
specificity of the score system for predicting the need of surgery is assessed
Time frame: before surgery
accuracy of the score system for predicting the need of surgery
accuracy of the score system for predicting the need of surgery is assessed
Time frame: before surgery
positive likelihood ratio of the score system for predicting the need of surgery
positive likelihood ratio of the score system for predicting the need of surgery is assessed
Time frame: before surgery
negative likelihood ratio of the score system for predicting the need of surgery
negative likelihood ratio of the score system for predicting the need of surgery is assessed
Time frame: before surgery
positive predictive value of the score system for predicting the need of surgery
positive predictive value of the score system for predicting the need of surgery is assessed
Time frame: before surgery
negative predictive value of the score system for predicting the need of surgery
negative predictive value of the score system for predicting the need of surgery is assessed
Time frame: before surgery
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