Effect of Antiviral Therapy on HVPG in Patients With Viral Cirrhosis

Inclusion Criteria: * Patients with viral cirrhosis were diagnosed; * Age 18-80 years; * Need and willing to accept measure HVPG; * First HVPG measurement of more than 5 mmHg; * Signed Informed Consent Exclusion Criteria: * Patients with viral cirrhosis have been treated with antiviral therapy and have achieved virological response; * Ready to accept or have accepted a TIPS procedure; * Splenic embolization was performed; * Inaccurate measurement of HVPG due to combined hepatic venous shunt; * Complicated with alcoholic liver disease, autoimmune liver disease or other types of liver disease; * Complicated with liver cancer or other organ malignancy; * Combined with severe cardiopulmonary disease affects survival; * Complicated with severe renal insufficiency; * Concomitant portal vein cavernous degeneration or extensive portal vein thrombosis; * Women who are planning to become pregnant or who are pregnant or breastfeeding.