Sleep Apnea Syndrome (SAS) is highly prevalent in acute stroke and it is related to worst outcome. We aim to assess if SAS treatment, started immediately after acute ischemic stroke, impacts infarct growing and clinical prognosis.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
60
AirCurve 10CS PaceWave (Resmed)
Meseguer
Paris, France
Infarct progression
Ischemic size at 7 days compared to ischemic size at admission on brain MRI
Time frame: 7 days
Neurological outcome
modified Rankin score (mRS), from 0 (no disability) to 6 (dead)
Time frame: 3 months
Neurological outcome on NIHSS
National Institute of Health Stroke Scale (NIHSS), from 0 (normal neurological examination) to 42
Time frame: 3 months
Duration of Auto-adaptative Servo-Ventilation use
mean duration per night auto-adaptative servo-ventilation was used during 7 days
Time frame: 7 days
SAS prevalence
assessed by respiratory polygraphy
Time frame: 3 months
SAS severity
assessed by apnea-hypopnea-index meseared by respiratory polygraphy, mild if AHI is 5-15/h, moderate if AHI is 15-30/h and severe if AHI is \> 30/h
Time frame: 3 months
Central apnea index
assessed by respiratory polygraphy
Time frame: 3 months
Obstructive apnea index
assessed by respiratory polygraphy
Time frame: 3 months
Quality of life on SF-12 questionnaire
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SF-12 (Short Form Survey 12) questionnaire (not a scale, result is shown as 2 numbers (physical and mental component scores) : if superior to 50, the quality of life is better to the mean quality of life in general population, if less than 50, the quality of life is worse than in the general population)
Time frame: 3 months
Quality of sleep on Pittsburgh Sleep Quality Index
Pittsburgh Sleep Quality Index, from 0 (good quality of sleep) to 21 (bas quality of sleep)
Time frame: 3 months
Daytime Sleepiness
Epworth Sleepiness Scale, from 0 (no sleepiness) to 24 (great sleepiness), sleepiness if \> 10
Time frame: 3 months