The study evaluated the effect of local application of simvastatin around immediate implant on the amount of gap fill, ridge dimensional alterations and bone density in humans.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
10
single injection of simvastatin gel in the gap around immediately placed implant
single injection of the solid lipid nanoparticle carrier in the gap around immediately placed implant
Effect of simvastatin on gap fill
using cone beam computed tomography
Time frame: 3 months after implant placement
Effect of simvastatin on horizontal ridge dimension
using cone beam computed tomography
Time frame: 3 months after implant placement
Effect of simvastatin on crestal bone level
using cone beam computed tomography
Time frame: 3 months after implant placement
Effect of simvastatin on bone density
using cone beam computed tomography
Time frame: 3 months after implant placement
Quality of wound healing
wound healing index
Time frame: 1 week after implant placement
Quality of wound healing
wound healing index
Time frame: 2 weeks after implant placement
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