Sarcopenia is defined by the reduction in skeletal muscle mass and physical performance. It results in a decrease in muscle strength, overall physical activity, walking and the development of balance disorders and falls. It is one of the natural consequences of aging and contributes to frailty and the appearance of geriatric syndrome (s) (Chandapasirt et al, 2015; Cruz-Jentoft et al, 2010). Its prevalence in patients with Head \& Neck cancer is 39% (Hua et al, 2020) and is associated with an increase in postoperative complications (Achim et al, 2017; Bril et al, 2019), with greater toxicity of chemotherapy. (Wendrich et al, 2017) and reduced overall survival (Hua et al, 2020). It is measured by CT scan (assessment of muscle volume with respect to L3 using IMAGE J software) (Teigen et al, 2018) and by clinical tests (performance tests) (Swartz et al, 2016, Cruz-Jentoft et al, 2010). Several studies have shown a possible assessment of sarcopenia by measuring skeletal muscle mass with regard to C3 (Ufuk et al, 2019; Swartz et al, 2016). This trial aims to evaluate the prevalence of sarcopenia in head and neck cancer evaluated by CT at C3.
Study Type
OBSERVATIONAL
Enrollment
50
evaluation of sarcopenia by CT san at the C3 vertebrae
Clinique Victor Hugo / Centre Jean Bernard
Le Mans, France
RECRUITINGAssessment of the prevalence of sarcopenia by cervical CT scan (C3)
Number of patients with sarcopenia at diagnosis and during treatments
Time frame: 6 months
Assessment of hypoalbuminemia
Number of patients presenting an hypoalbuminemia.
Time frame: 6 month
De- and undernutrition
Number of patients with a BMI \<18 and with a prescription for nutritional complements.
Time frame: 6 month
Compliance to the treatment
Number of patients having the complete planned treatment
Time frame: 6 months
complete response rate
Number of patients with a complete response on the end-of-treatment evaluation scanner according to the RECIST or PERCIST criteria in the numerator out of the total number of patients in the denominator
Time frame: 6 months
Assessment of hospitalizations treatment-related complications
Number of hospitalizations per patient for treatment-related complications
Time frame: 6 months
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