Clinical Investigation on the Safety and Clinical Performance of Papix Acne Scar.

Inclusion Criteria: 1. Subject's or parents or guardian (depending on the age of the subject) written informed consent obtained prior to any study-related procedures; 2. Male or female subjects aged ≥ 12 years of any race; 3. Subjects with any Fitzpatrick skin phototype; 4. Subjects with clinical diagnosis of mild to moderate acne vulgaris (IGA score 2 or 3) on the face; 5. Presence of acne scars (all types included), of grade mild or moderate according to SGA; 6. Subjects with cooperative attitude, able to comprehend the full nature and the purpose of the investigation, including possible risks and side effects, and able to comply with the requirements of the entire investigation (including ability to attend the planned visits according to the time limits), based on Investigator's judgement. Exclusion Criteria: 1. Pregnant women 2. Severe acne at inclusion or any acne requiring systemic treatment; 3. Presence of facial warts or fungal infections; 4. Active dermatitis on the face, rosacea, active herpes simplex; 5. Keloids presence in the area to be treated or keloids development during the treatment period; 6. History of radiation or skin tumors in the/close to the area to be treated in the past 5 years; 7. Laser ablative procedures within the last month; 8. Chemical peels within the last 6 months; 9. Use of topical treatments like antibiotics, corticosteroids, benzoyl peroxide, azelaic acid, hydroxy acids and other antinflammatory drugs within 2 weeks; 10. Use of topical retinoids within 4 weeks; 11. Use of systemic corticosteroids or antibiotics in the previous 30 days; 12. Use of systemic spironolactone/drospirenone or immunomodulators in the previous 3 months; 13. Use of oral retinoids or cyproterone acetate/chlormadinone acetate in the previous 6 months; 14. Use of scrub, alpha hydroxy acid (AHA), skin irritant products in the 2 days before study treatment start; 15. Subjects with any other clinically significant or unstable concurrent disease or skin condition or general condition that, in the Investigator's opinion, might interfere with the study evaluations; 16. Allergy, sensitivity or intolerance to the components of the investigational device formulations ingredients; 17. Concomitant or previous participation in other interventional clinical study in the past 3 months; 18. Subjects planning sun exposure or tanning booths or UV sources throughout the course of the study. In case of sun exposure this shall be limited and a protection cream (SPF 50+) shall be applied.