To determine the adequacy of EUS-LB using a 19G core needle compared to a 22G core needle in a prospective randomized study.
The 19Gauge core and 22Gauge core needles have both been used for EUS-LB with good success. Previous studies have reported good safety and tissue adequacy with both the needles, but the head-on comparison between these two needles is lacking. This is a prospective randomized trial comparing the biopsy specimen adequacy of 19Gauge versus 22Gauge core needles for EUS-LB.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
42
Geisinger Medical Center
Danville, Pennsylvania, United States
Length of Longest Piece
Length of the longest piece of the liver tissue obtained
Time frame: Up to 5 Days
Aggregate Specimen Length
Cumulative length of all the pieces of tissue obtained
Time frame: 3 to 5 Days
Degree of Fragmentation
Size of the fragments of the samples will be measured, then classified as small (\<5 mm), medium (5-8 mm) or large (\>8 mm), then compared for the 2 needles
Time frame: 3 to 5 Days
Number of Portal Tracts in the Specimen
Number of portal triads will be counted in the specimens and compared for the 2 needles
Time frame: 3 to 5 Days
Adverse Events and Serious Adverse Events
Untoward, undesired, or unplanned event
Time frame: 7 to 10 Days Post Procedure
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