The study aims to test whether platelet transfusion or fibrinogen concentrate is the most effective treatment of intraoperative bleeding, when performing open heart surgery with cardiopulmonary bypass on children with congenital heart defects.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
40
Platelets (10 ml/kg body weight) is transfused.
Fibrinogen concentrate (300 mg/kg body weight) is administered.
Sahlgrenska University Hospital
Gothenburg, Sweden
RECRUITINGHEPTEM-A10
The outcome measure is a measure of global coagulation efficacy, obtained by ROTEM analysis.
Time frame: 45 minutes after intervention
Amount of transfused packed red blood cells
Time frame: up to first postoperative morning
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