18F-DCFPyL PET/MRI in Regional Nodal&Distant Metastases Detection in Intermediate &HR Prostate Cancer

Inclusion Criteria: 1. Patient is older than 18-year-old 2. Biopsy proven prostate adenocarcinoma 3. Planned prostatectomy with lymph node dissection 4. Intermediate to high-risk disease (as determined by elevated Prostate-specific antigen (PSA) \[PSA\>10\], T-stage \[T2b or greater\], Gleason score \[Gleason score \> 6\] or other risk factors) 5. Able to provide written consent 6. Karnofsky performance status of ³50 (or Eastern Cooperative Oncology Group (ECOG) /World Health Organization (WHO) equivalent) Exclusion Criteria: 1. Neoadjuvant chemotherapy or radiation therapy prior to prostatectomy including focal ablation techniques (HiFu) 2. Androgen deprivation therapy or other neoadjuvant treatments prior to PET imaging surgery 3. Metallic implants (contraindicated for MRI)