Retrospective and confounder adjusted comparison of perioperative and longterm outcomes of patients requiring an esophagectomy for esophageal cancer with and without concomitant liver cirrhosis.
Study Type
OBSERVATIONAL
Enrollment
170
retrospective comparison of esophagectomy for esophageal cancer in patients with or without concomitant liver cirrhosis
University of Hamburg Medical Institutions
Hamburg, Germany
Long-term survival
Time frame: 5 years
Major complication
Clavin Dindo ≥ 3
Time frame: 90 days postoperatively
Anastomotic leakage rate
Rate of endoscopically diagnosed anastomotic leakage
Time frame: 90 days postoperatively
Sepsis rate
Rate of participants with ≥ 2 points in Sepsis-related organ failure (SOFA) score within hospital stay
Time frame: 90 days postoperatively
Renal failure rate
Rate of acute kidney insufficiency (AKI) II-III (AKI Kidney Disease: Improving Global Outcomes (KDIGO) Guidelines)
Time frame: 90 days postoperatively
Hepatic failure rate
Number of participants with clinical diagnosis: coagulopathy, icterus and potentially hepatic encephalopathy
Time frame: 90 days postoperatively
Cardiac complication
cardiac complication requiring pharmacological treatment or intervention and / or ICU surveillance
Time frame: 90 days postoperatively
Chylus fistula rate
Concentration of triglycerides (TG) in drain fluids ≥ 3 times TGs i.s.
Time frame: 90 days postoperatively
Pulmonary complications
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Pneumonia requiring antibiotics, ventilatory insufficiency requiring supportive therapy
Time frame: 90 days postoperatively