The purpose of this research is to establish the normal range of diameter and distensibility of pylorus and the fasting and postprandial antro-pyloric motility in healthy adults.
An Endoflip catheter will be placed through the mouth into the stomach in order to measure distal antral contractile activity and pyloric diameter and distensibility during fasting and after the ingestion of a standard meal
Study Type
OBSERVATIONAL
Enrollment
30
Endoflip device to measure gastric and pyloric functions
Michael Camilleri
Rochester, Minnesota, United States
fasting and postprandial pyloric diameter
Change in Pyloric diameter will be measured during fasting and postprandial using Endoflip
Time frame: 1 hour prior to meal and 1 hour following standardized meal
fasting and postprandial pyloric distensibility index
Change in Pyloric distensibility index will be measured during fasting and postprandial using Endoflip
Time frame: 1 hour prior to meal and 1 hour following standardized meal
fasting and postprandial distal antral motility index
Change in distal antral motility index will be measured during fasting and postprandial using Endoflip
Time frame: 1 hour prior to meal and 1 hour following standardized meal
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