An exploratory study to evaluate the Effect of Improving Glycemic Variability of Anagliptin Compared with Sitagliptin in Patients with Type 2 Diabetes Mellitus
This clinical trial is an exploratory study, and does not calculate the subject number based on statistical assumptions, and enrolls 50 subjects per group and a total of 100 subjects are registered to evaluate the effect of improving blood glucose variability in type 2 patients with anagliptin 100 mg twice a day(BID) and sitagliptin 100 mg once a day(QD).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
89
Continuous Glucose Monitoring with Anagliptin 100mg BID or Sitagliptin 100mg QD treatment for 12 weeks
Kangdong Sacred Heart Hospital
Seoul, South Korea
Effect of Improving Glycemic Variability
Mean amplitude of glycemic excursion (MAGE)
Time frame: 3 days after 12 weeks treatment
Average nighttime (18:00~07:59) blood glucose change after 12 weeks compared to baseline
after 12 weeks compared to baseline in the test group and the control group
Time frame: after 12 weeks treatment
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