Clinical Study of CAR-iNKT Cells in the Treatment of Relapsed/Refractory/High-risk B-cell Tumors

Inclusion Criteria: * Male or female patients aged 5-70 years; * The patient's ECOG score was ≤2, and the expected survival time of \> was 12 weeks. * The patient was diagnosed with B-cell tumor by pathological and histological examination and had no effective treatment options, such as recurrence after chemotherapy or hematopoietic stem cell transplantation. Or the patient voluntarily chooses the infusion of CAR-INKT cells as the first treatment. * B cell tumors include the following three types: 1. B-cell acute lymphocytic leukemia (B-ALL); 2. Inert B-cell lymphoma (CLL, FL, MZL, LPL, HCL); 3. Aggressive B-cell lymphoma (DLBCL, BL, MCL); * Subject: 1. Residual lesions remain after primary treatment and are not suitable for HSCT (Auto/Allo-HSCT); 2. relapse after complete response (CR1) and unsuitable for allogeneic/autologous HSCT; 3. Patients with high risk factors; 4. relapse or no remission after hematopoietic stem cell transplantation or cellular immunotherapy. * having measurable or evaluable lesions; * The main tissues and organs of the patient function well: 1. Liver function: ALT/AST \< 3 times the upper limit of normal (ULN); 2. Renal function: creatinine \< 220μmol/L; 3. Lung function: indoor oxygen saturation ≥95%; 4. Heart function: left ventricular ejection fraction (LVEF) ≥40%. * Patients or their legal guardians voluntarily participate and sign the informed consent. Exclusion Criteria: * Pregnant or lactating women, or women who plan to become pregnant within six months; * Infectious diseases (e.g. HIV, active hepatitis B or C infection, active tuberculosis, etc.); * GVHD; * Abnormal vital signs and failure to cooperate with the examination; * People with mental or mental illness who are unable to cooperate with treatment and efficacy evaluation; * People with high allergic constitution or severe allergic history, especially those allergic to IL-2; * Subjects with systemic infection or severe local infection need anti-infection therapy; * Complicated with dysfunction of heart, lung, brain, liver, kidney and other important organs; * Any unstable systemic disease: including but not limited to unstable angina pectoris, cerebrovascular accident or transient cerebral ischemia (within 6 months before screening), myocardial infarction (within 6 months before screening), congestive heart failure (NYHA classification ≥III); * Doctors believe that there are other reasons for not being included in treatment.