Hypophosphatemia and Bronchiolitis

Hospices Civils de Lyon400 enrolled

Overview

Bronchiolitis is a major public health problem and the leading cause of paediatric intensive care unit admission in infants. Hypophosphatemia is common in adult intensive care units and was associated with an increase of the duration of mechanical ventilation and the length of stay. Our hypothesis is that hypophosphatemia is common in bronchiolitis and could be a marker of severity.

Study Type

OBSERVATIONAL

Enrollment

400

Conditions

Hypophosphatemia Bronchiolitis

Interventions

hypophosphatemia occurrence in infants with severe bronchiolitis admitted in a pediatric intensive care unitBIOLOGICAL

Serum phosphorus level \< 1.55 mmol/L at any time between admission and the 5th day.

Eligibility

Sex: ALLMin age: 7 DaysMax age: 3 Months

Medical Language ↔ Plain English

Inclusion Criteria: * Age \> 7 days and \< 3 months of life * Admission to the pediatric intensive care unit from 01/11/2016 to 31/03/2020 * With a diagnosis of moderate to severe bronchiolitis according to HAS 2019 criteria Exclusion Criteria: * Renal Failure and tubulopathy * Previous disorder of phospho-calcium balance * Malignant pathology * Lenght of stay less than 24 hours * History of cardiac, aortic or hepatic surgery

Locations (1)

Hopital Femme Mere Enfant - Groupement Hospitalier Est

Bron, France

RECRUITING

Outcomes

Primary Outcomes

hypophosphatemia occurrence in severe bronchiolitis in infants admitted in a pediatric intensive care unit

A serum phosphorus level\< 1.55mmol/L defines the hypophosphatemia.

Time frame: At any time in the first 5th days after Pediatric intensive care admission

Central Contacts

Florent Baudin, Dr

CONTACT

4 72 12 97 35 florent.baudin@chu-lyon.fr

Data from ClinicalTrials.gov

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