The Mass Balance and Biotransformation of [14C]Donafenib in Healthy Adult Man

Inclusion Criteria: * A healthy male adult. * Age is between 18 and 45, inclusive. * Body mass index is between 19 and 26, inclusive. * Voluntarily to provide informed consent form. * Willing and able to communicate with investigators and complete the trial according to clinical trial protocol. Exclusion Criteria: * Any abnormal and clinical significant findings. * A positive examination result of HBsAg/HBeAg, HIV antibody and treponema pallidum antibody. * Volunteers who had participated in a radiolabeled clinical study or were exposed to significant levels of radiation for any reasons within the 12 months prior to the study. * Volunteers who had used of prescription or herbal products that may affect the drug metabolism within 30 days before the study. * Volunteers who had blood loss/donation up to 400 mL within 3 months before the screening, or received blood transfusion within 1 month.