Patients with both, migraine and endometriosis, present the case-group, while women with endometriosis without migraine serve as controls. The primary endpoint is endometriosis stage confirmed by laparascopy compared to the control group. Further points to compare between groups are infertility, dysmenorrhea, dyschezia, dyspareunia, number of operations, family history with first-degree relatives, and age of first symptoms for both conditions and age at first operation. Secondary endpoints to evaluate in percentages within the migraine group are migraine frequency, migraine aura/non-aura, age at migraine start, hormonal migraine, family history, treatment response, response to prophylactic agents, localization, types of aura and triggers. Other medical conditions and comorbidities like depression will be noted as well as response to Dienogest treatment. In the questionnaire we will ask 62 Questions overall. The Questions for endometriosis are based on a questionnaire from the world endometriosis research foundation and to evaluate the severity of the migraine we will use the MIDAS (Migraine Disability Assessment) questionnaire (8).
Study Type
OBSERVATIONAL
Enrollment
344
only questionaire
Universitätsspital Zürich
Zurich, Switzerland
Endometriosis stage
endometriosis stage confirmed by laparascopy compared to the control group
Time frame: 4 years
infertility, dysmenorrhea, dyschezia, dyspareunia, number of operations
s.o.
Time frame: 4 years
and age of first symptoms for both conditions and age at first operation
s.o.
Time frame: 4 years
family history with first-degree relatives,
s.o.
Time frame: 4 years
Secondary endpoints to evaluate in percentages within the migraine group are migraine frequency, migraine aura/non-aura, age at migraine start, hormonal migraine, family history, treatment response,
s.o.
Time frame: 4 years
response to prophylactic agents, localization, types of aura and triggers. Other medical conditions and comorbidities like depression will be noted
s.o.
Time frame: 4 years
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