This study is implemented in association with the study "J-TAIL-2" ; prospective multicenter observational study of atezolizumab in patients with unresectable, locally advanced or metastatic non-small cell lung cancer, UMIN study ID: UMIN000041263, to evaluate biomarkers for selection of appropriate patients in treatment with atezolizumab combination therapy.
Study Type
OBSERVATIONAL
Enrollment
470
Correlation between PD-L1 SNP and atezolizumab combination therapy
Time frame: Baseline
Correlation between rate of change in plasma protein expression level and atezolizumab combination therapy
Time frame: Baseline, Predose of cycle 2 (each cycle is 21 days), and when immune-related adverse event occurs (through study completion, an average of 2 years 5 months)
Correlation between an immune microenvironment of small cell lung cancer and atezolizumab combination therapy
Time frame: Baseline
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Hyogo Cancer Center
Akashi, Japan
Asahikawa Medical University Hospital
Asahikawa, Japan
National Hospital Organization Asahikawa Medical Center
Asahikawa, Japan
Juntendo University Hospital
Bunkyō City, Japan
Nippon Medical School Hospital
Bunkyō City, Japan
Tokyo Medical And Dental University, Medical Hospital
Bunkyō City, Japan
Chiba University Hospital
Chiba, Japan
National Cancer Center Hospital
Chūōku, Japan
Fukuoka University Hospital
Fukuoka, Japan
National Hospital Organization Kyushu Cancer Center
Fukuoka, Japan
...and 85 more locations