Study of the Influence of Liver Function on Blood Concentrations of Runcaciguat in Participants With Different Degrees of Liver Impairment

Inclusion Criteria: Age * Participant must be 18 to 79 years of age (inclusive) at the time of signing the informed consent. Weight * Body mass index (BMI) within the range 18 to 35 kg/m\^2 (inclusive). Sex and Contraceptive/Barrier Requirements * Male and female white participants. Main Inclusion Criteria for participants with hepatic impairment * Participants with hepatic impairment (Child Pugh A or B). * Participants with stable liver disease in the last 2 months. Main Inclusion Criteria for control group of participants * Healthy male and female white participants. * Mean age and body weight in the control group and in the two groups with hepatic impairment (Child Pugh A and B) should not vary by more than ±10 years and ±10 kg. * Gender-matched. Exclusion Criteria: Main exclusion Criteria for all participants Medical and surgical history * Participants with a medical disorder, condition, or history of such that would impair the participant's ability to participate or complete this study in the opinion of the investigator or the sponsor. Medication, drug use and special behavioral patterns * Suspicion of drug or alcohol abuse. Other * Participation in another clinical trial within 3 months (for previous multi-dose study) or 1 month (for previous single dose study) before dosing. * Exclusion periods from other studies or simultaneous participation in other clinical studies. coronavirus disease 2019 (COVID-19) specific exclusion criteria * History of COVID-19. * Contact with severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) positive or COVID-19 patient within the last 4 weeks prior to admission to the clinical unit * Positive SARS-CoV-2 viral polymerase chain reaction (PCR) test Main exclusion Criteria for participants with hepatic impairment Medical and surgical history * Pre-existing diseases beside hepatic impairment for which it can be assumed that the absorption, distribution, metabolism, elimination and effects of the study drugs will not be normal. * Evidence of hepatic encephalopathy related to chronic liver disease \> grade 2 (exclusion by Number Connection Test). * Congestive heart failure of New York Heart Association grade III or IV. * History of conspicuous bleeding within the past 3 months. * Severe arrhythmia requiring antiarrhythmic treatment within the past 3 months. * Participants with diabetes mellitus with a glycohemoglobin A1c (HbA1c) \>9%. * Severe ascites of more than 6 L (estimated by ultrasound). * Participants with primary and secondary biliary cirrhosis. * Participants with sclerosing cholangitis. Electrocardiogramm (ECG), blood pressure, heart rate * Systolic blood pressure below 100 mmHg or above 169 mmHg. * Diastolic blood pressure below 50 and above 95 mmHg. * Resting heart rate below 50 beats per minute (bpm) or above 95 bpm. Laboratory examination * Platelet count \< 40 x 10\^9/L. * Hemoglobin \<9 g/dL. * Alkaline phosphatase (AP) ≥ 4 times the upper limit of normal (ULN). * Aspartate aminotransferase (AST) or alanine aminotransferase (ALT) in conjunction with gamma glutamyl transpeptidase (GGT) ≥4 times the ULN (an isolated elevation of GGT above 4 times ULN will not exclude the participant). * Serum albumin \<20 g/L. * Prothrombin time (Quick test) \<40%. * Renal failure with an estimated glomerular filtration rate (eGFR) ≤ 40 mL/min/1.73 m\^2 (according to CKD-EPI equation). Main Exclusion criteria for control group of participants Medical and surgical history * A history of relevant diseases of vital organs, the central nervous system, or other organs. * Liver insufficiency or active liver disease, which may include unexplained persistent transaminase elevations. * Renal impairment with an estimated glomerular filtration rate (eGFR) ≤80 mL/min/1.73 m\^2 (according to CKD-EPI equation). * Known or suspected liver disorders (e.g. Morbus Gilbert/Meulengracht) and bile secretion/flow (cholestasis, also history of it). Medication, drug use and special behavioral patterns * Regular use of therapeutic or recreational drugs, e.g. carnitin products, anabolics, high dose vitamins. Laboratory examination * Relevant deviation from the normal range in clinical chemistry (including thyroid stimulating hormone \[TSH\]), hematology, coagulation or urinalysis as judged by the investigator. * Increase of liver enzymes (e.g. ALT, AST, alkaline phosphatase, gamma glutamyl transpeptidase or total bilirubin) above ULN. * Increase of lipase and amylase (despite isolated marginal increases of lipase or amylase to account for variability of the parameters, and the participant is asymptomatic and has no other laboratory changes assuming disease based on medical judgment). * Positive results for hepatitis B virus surface antigen (HBsAg), hepatitis C virus antibodies (anti-HCV), human immune deficiency virus (HIV) antibodies 1+2/HIV p24 antigen (HIV-1/2 combi test). Electrocardiogramm (ECG), blood pressure heart rate * Systolic blood pressure below 100 or above 145 mmHg at screening. * Diastolic blood pressure below 50 or above 95 mmHg at screening. * Resting heart rate below 50 or above 95 bpm at screening.