To investigate whether perioperative electroacupuncture is more effective than postoperative electroacupuncture in improving gastrointestinal function after colorectal cancer operation
Although there are large intestine cancer postoperative clinical research of acupuncture, but fewer sample size, whether perioperative acupuncture intervention is superior to the postoperative acupuncture intervention, remains to be seen, so investigators proposed to carry out the preliminary experiment, the data can be collected according to the different characteristics of perioperative, perioperative choose different acupoints compatibility, give full play to the needle medicine compound anesthesia in colorectal cancer surgery play a unique function of viscera protection, to explore the curative in colorectal cancer surgery perioperative intervened to promote the role of gastrointestinal function after surgery for early rehabilitation provides evidence-based medical evidence, develop and optimize the acupuncture and drugs combined anesthesia in colorectal cancer surgery perioperative application of specification, It promoted the establishment of the first treatment mode of "accelerated recovery in perioperative period of colorectal cancer operation based on combined acupuncture and drug anesthesia"
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
30
Routine perioperative management： All patients were given perioperative fluid rehydration and nutritional support to correct acid-base imbalance, electrolyte disturbance, anti-infection, hemostasis and other symptomatic treatment； electroacupuncture protocol： Preoperation:RN 6 + RN 4 +ST30 + ST 36+ Hegu (bilateral),De qi, electroacupuncture, continuous wave, 5Hz, 30min before surgery at 19:00 PM Inoperatively: LI 4+ PC 6 + ST36 + GB 34 (bilateral) ,Deqi, electroacupuncture with density wave, 2/100Hz, 30 minutes before operation to the end of the operation Postoperative: LI 4 +SJ 6 + ST 6 + ST 37(Left);LI 4 +SJ 6 + ST 6 + ST 37(Right)(alternated on both sides per 12h) Deqi, electroacupuncture, continuous wave, 5Hz, 30min,19:00 on the left side and 07:00 on the next day after surgery,until to first flatus (FF)
Routine perioperative management： All patients were given perioperative fluid rehydration and nutritional support to correct acid-base imbalance, electrolyte disturbance, anti-infection, hemostasis and other symptomatic treatment； electroacupuncture protocol： Postoperative: LI 4 +SJ 6 + ST 6 + ST 37(Left);LI 4 +SJ 6 + ST 6 + ST 37(Right)(alternated on both sides per 12h) Deqi, electroacupuncture, continuous wave, 5Hz, 30min,19:00 on the left side and 07:00 on the next day after surgery,until to first flatus (FF)
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Shanghai, China
RECRUITINGtime to first flatus (TFF)
time to first flatus
Time frame: Day 3
Recovery time of postoperative bowel sounds
The enteric voice continuous auscultation recorder was used to monitor immediately after operation, and the time to the end of operation was calculated
Time frame: Day 3
Time of first postoperative defecation
Patients self-report their defecation and doctors record the time
Time frame: Day 3
Dietary recovery
First time of water intake, tolerance to liquid diet time, tolerance to solid diet time
Time frame: Day 3
Postoperative gastrointestinal dysfunction
Duration and frequency of postoperative appearance: nausea, emesis,ventosity
Time frame: Day 3
Quality of life scale 1
EORTC QLQ-C30（Version 3.0 European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (standard score, SS, range from 0 to 100, higher scores mean a better outcome);
Time frame: "Day 0"，"Day 3"，"Day 7"
Quality of life scale 2
SF-36(Chinese version),The Short Form (36) Health Survey,( The SF-36 consists of eight scaled scores, which are the weighted sums of the questions in their section. Each scale is directly transformed into a 0-100 scale on the assumption that each question carries equal weight. The lower the score the more disability. The higher the score the less disability)
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Time frame: "Day 0"，"Day 3"，"Day 7"
Postperation pain
VAS,Visual analogy score (0 to 10,higher scores mean a worse outcome)
Time frame: Day 3
Motor function
Walking independently after surgery
Time frame: Day 3
LOS(length of stay)
From admission to discharge
Time frame: Day 7
Biochemical indexes
C-reactive protein(CRP)，motilin(MTL).Gastrin(GAS),vasoactive peptide(VIP)
Time frame: "Day 0"，"Day 3"
Biochemical indexes 1
C-reactive protein(CRP, ug/L)
Time frame: "Day 0"，"Day 3"
Biochemical indexes 2
Motilin(MTL, ng/L)
Time frame: "Day 0"，"Day 3"
Biochemical indexes 3
Gastrin(GAS, ng/L)
Time frame: "Day 0"，"Day 3"
Biochemical indexes 4
vasoactive peptide(VIP, pg/L)
Time frame: "Day 0"，"Day 3"
Adverse Event Assessment
Any adverse events in the study
Time frame: "Day 0"，"Day 3"，"Day 7"