Effect of Oral Nutritional Supplements on Body Weight Loss of Patients With Nasopharyngeal Carcinoma

Inclusion Criteria: * Newly histologic diagnosis of nasopharyngeal carcinoma; * All genders, range from 18-70 years old; * Clinical stage II-IVa according to the 8th edition of the Union for International Cancer Control/American Joint Committee on Cancer (UICC/AJCC) staging system; * Patient-Generated Subjective Nutrition Assessment (PG-SGA) score ≤8; * Main organ functions test should be satisfied the following conditions: (1) Absolute neutrophil count (ANC) ≥1.5×10\^9/L; (2) Platelet (PLT) ≥80×10\^9/L; (3) Hemoglobin (Hb) ≥90 g/L; (4) Bilirubin \< 1.5 times the upper limit of normal value (ULN), aspartate aminotransferase (AST) and alanine aminotransferase (ALT) \< 2.5 times the upper limit of normal value; (5) Creatinine \< 1.5 times the upper limit of normal value or creatinine clearance rate \>60 ml/min. Exclusion Criteria: * Patients whose energy intake is less than 60% of the target energy requirement for 3 days or more; * Have or are suffering from other malignant tumors; * Refuse concurrent chemoradiotherapy; * With diabetics, galactosemia, or sever metabolic diseases or endocrine diseases; * Cannot take oral or enteral nutrition, including intestinal obstruction, severe short bowel syndrome or high output fistula, or with severe digestive system diseases; * Known allergic reaction to any component of Abbott®Ensure, or severe allergic constitution; * Pregnant or lactating women; * With previous or ongoing clinical trials; * Refuse to sign inform consent form.