Acute Anterior or Posterior Cerebral Artery Occlusion Recanalization Therapy and Relationships With Clinical Outcome (ACAPULCO)

Fondation Ophtalmologique Adolphe de Rothschild100 enrolled

Overview

Nearly 3% of patients with ischaemic stroke (IS) have an isolated occlusion of the anterior or posterior cerebral artery in the acute phase of the disease. In those patients, intravenous thrombolysis (IT) is indicated for 4.5 hours after symptoms onset. Due to a lack of data, mechanical thrombectomy (MT) is not considered as a gold standard to treat IS alone or in addition with IT. Therefore, observational studies are needed to understand the clinical evolution of patients with IS treated with IT and/or MT. The ACAPULCO retrospective observational study aims to highlight potential benefits of MT in those patients to improve their management and to propose targeted therapies in the future.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Ischemic Stroke Thrombi

Eligibility

Sex: ALLMin age: 18 YearsMax age: 95 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age ≥ 18 and \< 96 * Clinical signs consistent with acute ischemic stroke * Patients who presented within 6 hours of stroke symptoms onset * Isolated occlusion of the anterior or the posterior artery Exclusion Criteria: * Administration of recanalization treatment before hospital admission

Locations (1)

Outcomes

Primary Outcomes

Clinico-radiological evolution of IS patients with isolated occlusion of the anterior or posterior cerebral artery.

Good Neurological Condition Good neurological outcome (GNO) at 3 months will defined using the modified Rankin Scale (mRS). A normal/near normal outcome after procedure is associated with a mRS Scale score = 0-1 and severe disability/death is associated with a mRS Scale score = 5-6

Time frame: 90 days