Effects of Smoking State on Decision Making

Wake Forest University Health Sciences5 enrolled

Overview

Adult smokers will be tested using behavioral and neuroimaging measures after smoking as usual and after overnight abstinence.

Study Type

INTERVENTIONAL

Allocation

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Behavior

Interventions

smoking abstinenceOTHER

participants will be asked to not smoke for at least 12 hours

smoking satietyOTHER

participants will be asked to smoke as usual

Eligibility

Sex: ALLMin age: 18 YearsMax age: 55 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Aged 18-55 years * Smokes cigarettes or e-cigarettes * Negative urine drug screen Exclusion Criteria: * Unstable or serious medical or mental health condition * History of serious head trauma * Pregnancy * Unsuitable for MRI * Weight \> 350 pounds (maximum allowed for MRI)

Locations (1)

Wake Forest University School of Medicine

Winston-Salem, North Carolina, United States

Outcomes

Primary Outcomes

Effort based decision making

number of high effort selections

Time frame: through study completion, an average of 1 year

Distress tolerance behavior

duration on measures of distress tolerance

Time frame: through study completion, an average of 1 year

Data from ClinicalTrials.gov

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