Assessment of the Effect of Restriction on Alimentary AGE in Progression of Chronic Kidney Disease

N/ANot Yet RecruitingNCT04827290

Centre Hospitalier Saint Joseph Saint Luc de Lyon66 enrolled

Overview

Normal-protein and low-AGE through raw or rare proteins diet versus normal-protein and high-AGE diet in stage IIIa-b renal failure patients

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

Conditions

Kidney Failure, Chronic Chronic Kidney Disease stage3 Chronic Kidney Disease Stage 3B Chronic Kidney Disease Stage 3A (Disorder)Chronic Kidney Disease, Stage 3 (Moderate)Diet Habit

Interventions

Low-AGE dietBEHAVIORAL

Low-AGE diet during 24 months

High-AGE dietBEHAVIORAL

High-AGE diet during 24 months

Eligibility

Sex: ALLMin age: 18 YearsMax age: 89 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with a grade IIIA-B CKD (GFR with CKD-EPI ≥ 30 mL/min and \< 60mL/min) * Informed consent signed * Aged 18 to 89 years Exclusion Criteria: * Protected adult * Acute renal failure * Patient already on a low-AGE diet (\< 1kU AGE/day) following a dietetic consultation * Current participation in another interventional research

Locations (1)

Centre Hospitalier Saint Joseph Saint Luc

Lyon, France

Outcomes

Primary Outcomes

Glomerular Filtration Rate

Glomerular Filtration Rate estimated by the CKD-EPI formula with a blood sample

Time frame: At 24 months

Secondary Outcomes

Proteinuria

Proteinuria (g/24h) found in the 24-hour urine

Time frame: At 24 months

Central Contacts

Fanny Doroszewski

CONTACT

0033478618398 fdoroszewski@chsjsl.fr

Gabrielle Normand, MD

CONTACT

lgnormand@chsjsl.fr

Data from ClinicalTrials.gov

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