Impact of PD1-lymphocytes in Bronchoalveolar Lavage of Patients With Lung Cancer

University of Vienna40 enrolled

Overview

The aim of this trial is to assess PD1-lymphocytes in bronchoalveolar lavage in patients with lung cancer, ILD and asthma.

In this trial, 20 patients with lung cancer, 10 patients with asthma and 10 patients with interstitial lung disease who have to undergo bronchocospy for medical reasons are enrolled. In each patient, bronchoalveolar lavage is performed to assess PD1-lymphocytes.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Lung Cancer

Interventions

bronchoalveolar lavageDIAGNOSTIC_TEST

Bronchoalveolar lavage is performed by instillation and suction of saline in the middle lobe during bronchoscopy. Cytological examination and flow cytometry will be performed to assess PD-1lymphoctes.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * age \>18 years * patients with lung cancer, asthma or ILD and indication for bronchoscopy for medical reasons * Ability to provide informed consent Exclusion Criteria: * acute excacerbation in patients with asthma or ILD * endoluminal tumor growth or penumonia in patients with lung cancer

Locations (1)

Medical University of Vienna

Vienna, Austria

RECRUITING

Outcomes

Primary Outcomes

To assess and compare PD1-lmyphocytes in bronchoalveolar lavage in patients with malignant and benign lung diseases to evluate their impact in lung cancer patients

Time frame: 6 months

Central Contacts

Daniela Gompelmann

CONTACT

0043 1 40400 47730 daniela.gompelmann@meduniwien.ac.at

Data from ClinicalTrials.gov

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