This investigations aims to investigate whether supplementation with antioxidant vitamins (vitamin C and vitamin E) can influence, enhancing or blocking, the hypertrophic adaptations caused by strength training in sedentary subjects.
A randomized, double-blind, placebo-control controlled trial will be conducted. In a previous session volunteers will be interviewed to determine if they meet the inclusion criteria. Will be done two weeks of flushing out other types of supplementation and strenuous physical exercise, along with familiarization with the strength training program and performance tests to be carried out during the rehearsal. Subsequently, it will be a week without exercising to start with the experimental designs. From the start of the trial, participants should avoid physical exercise. strenuous outside the training protocol and if usual, they will only be able to perform one resistance training session per week. Participants should avoid ingesting of foods that contain high amounts of antioxidant compounds: more than two juices of fruits, more than four cups of coffee or tea. Juices with high antioxidant content should be avoided. Alcoholic beverages should also be avoided. * Group 1 (G1): Antioxidant vitamins (VitC (1000 mg) + VitE (235 mg)) + exercise * Group 2 (G2): Placebo + exercise A supplementation period of 12 weeks will be carried out. In each period, supplementation with antioxidant vitamins: VitC (1000 mg) + VitE (235 mg) or with placebo. All participants will ingest the supplementation between 1-3 hours before training, the days of rest in the mornings. All participants will perform a 12-week strength training protocol. The training session performed in the sharp design will be the first training session in chronic design. Being the baseline (E0) and post-exercise (E1) assessment performed in G1, G2 and G3 also the first evaluation corresponding to the chronic design. In the middle of the supplementation period (week 6) and at the end, two new evaluations (week 12). Baseline evaluations will be performed prior to an exercise session of week 6 (E2) and at the last exercise session (E3) of the following parameters: performance physique, body composition, micronutrient analysis, muscle ultrasound. I also know conduct post-exercise physical performance assessments Figure 2. The strength training protocol will be carried out 4 days a week at the facilities sports of the European University. The sessions will be planned by a professional from the Sciences of Physical Activity and Sports. Sessions will be tracked through a diary.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Enrollment
30
1000 mg 235 mg
Placebo
Universidad Europea de Madrid
Madrid, Spain
DEXA
Evaluation of muscle mass with dual energy X-ray absorptiometry
Time frame: Week 0
DEXA
Evaluation of muscle mass with dual energy X-ray absorptiometry
Time frame: Week 10
Anthropometry
Evaluation of muscle mass by a ISAK 1 level anthropometrist
Time frame: Week 0
Anthropometry
Evaluation of muscle mass by a ISAK 1 level anthropometrist
Time frame: Week 5
Anthropometry
Evaluation of muscle mass by a ISAK 1 level anthropometrist
Time frame: Week 10
Bioimpedance
Evaluation of muscle mass with an Inbody
Time frame: Week 0
Bioimpedance
Evaluation of muscle mass with an Inbody
Time frame: Week 5
Bioimpedance
Evaluation of muscle mass with an Inbody
Time frame: Week10
DOMS
Delayed onset muscle soreness evaluated with visual analoguic scale (0 no pain- 10 maximal pain)
Time frame: Week 0
DOMS
Delayed onset muscle soreness evaluated with visual analoguic scale (0 no pain- 10 maximal pain)
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Time frame: Week 5
DOMS
Delayed onset muscle soreness evaluated with visual analoguic scale (0 no pain- 10 maximal pain)
Time frame: Week 10
Manual dinamometry
Handgrip
Time frame: Week 0
Manual dinamometry
Handgrip
Time frame: Week 5
Leg dinamometry
Dinamometer
Time frame: Week 0
Leg dinamometry
Dinamometer
Time frame: Week 5
Leg dinamometry
Dinamometer
Time frame: Week 10
RPE
10-point scale (no exertion 0- maximal effort 10)
Time frame: Week 0
RPE
10-point scale (no exertion 0- maximal effort 10)
Time frame: Week 5
RPE
10-point scale (no exertion 0- maximal effort 10)
Time frame: Week 10
1 RM
Bench press and squats
Time frame: Week 0
1 RM
Bench press and squats
Time frame: Week 5
1 RM
Bench press and squats
Time frame: Week 10
Parameters determined by ENCODER
Bench press and squats
Time frame: Week 0
Parameters determined by ENCODER
Bench press and squats
Time frame: Week 5
Parameters determined by ENCODER
Bench press and squats
Time frame: Week 10