Hypnosis for Chronic Idiopathic Pruritus

Centre Hospitalier Universitaire de Nice12 enrolled

Overview

Chronic idiopathic pruritus (CIP) is a frequent and disabling condition, for which there is no specific treatment. It was shown previously that hypnosis can relieve painful sensations. Pain and pruritus share many similarities regarding sensory receptors and pathways, suggesting that hypnosis might help relief CIP.

Chronic idiopathic pruritus (CIP) is a frequent and disabling condition, with significative impact on quality of life. At present, there is no specific treatment for CIP. Topical steroids are frequently used, with partial efficacy, and adverse effects. Hypnosis is a specific state of conscience. It differs from waking state, sleeping state, relaxation, or meditation. In this state, the person is highly responsive to suggestion. In medicine, hypnosis can be used to engage the internal resources of the person against unpleasant feelings. It was shown previously that hypnosis can relieve painful sensations. Pain and pruritus share many similarities regarding sensory receptors and pathways, suggesting that hypnosis might help relief CIP.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Chronic Idiopathic Pruritus

Interventions

HypnosisOTHER

Chronic idiopathic pruritus is treated by hypnosis

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Male or female of at least 18 years at screening * Diagnosis of chronic (at least 6 wks.) idiopathic pruritus * Pruritus Numeric Rating Scale \> = 4 Exclusion Criteria: * Pruritus caused by a dermatological or a systemic conditions * Suicidal crisis, moderate, or severe * Psychosis (schizophrenia, persistent delusional disorder) * Bipolar disorder, not stabilized or decompensating * Personality disorder, decompensated

Locations (1)

Chu de Nice

Nice, France

Outcomes

Primary Outcomes

Change From Baseline in Pruritus Numeric Rating Scale

Assessment of the intensity of pruritis in Pruritus Numeric Rating Scal; the minimum and maximum values 0 to 10

Time frame: Day 84

Secondary Outcomes

Change From Baseline in Pruritus Verbal Rating Scale

Assessment of Pruritus by pruritus Verbal Rating Scale; the minimum and maximum values 0 to 4

Time frame: Day 84

Change From Baseline in Sleeping Scale

assessment in sleeping scale ; the minimum and maximum values 0 to 10

Time frame: Day 84

Change From Baseline in DLQI scale

assessment in DLQI scale; result between 0 to 30

Time frame: Day 84

Change From Baseline in HAD scale

assessment in HAD scale; result between 0 to 42

Time frame: Day 84

Change From Baseline in usage of topical steroids

assessment in usage of topical steroids

Time frame: Day 84

Evaluation of tolerance of hypnosis

assessment of tolerance of hypnosis with report of adverse event

Time frame: Day 84

Data from ClinicalTrials.gov

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