NIV Prevents Post-operative Respiratory Failure After Bariatric Surgery

University of Campania Luigi Vanvitelli107 enrolled

Overview

Postoperative non-invasive ventilation (NIV) has been proposed as an attractive strategy to reduce morbidity and improve postoperative outcomes in obese subjects undergoing general anesthesia. Bariatric patients present a peculiar negative feature; the increased body mass index (BMI) correlates with loss of perioperative functional residual capacity (FRC), expiratory reserve volume (ERV) and total lung capacity (TLC), decreased up to 50% of preoperative values. The aim of the current randomized trial is to evaluate the efficacy of NIV in post-anaesthesia care unit (PACU) in reducing post-extubation acute respiratory failure and the consequent admission in intensive care units (ICU) after BIBP in obese adult patients.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

107

Conditions

Obesity Postoperative Respiratory Distress

Interventions

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Morbid Obesity * Patients undergoing Biliointestinal Bypass (BIBP) Exclusion Criteria: * Patients requiring emergency operation with rapid sequence induction * Patients with suspected presence of difficult airway or pre-existing lung impairment * Pregnancy * Asthma * Severe renal dysfunction, * cardiac disease resulting in marked limitation of physical activity, corresponding to NYHA class \>II

Outcomes

Primary Outcomes

Intensive care unit admission rate

The primary outcome was the evaluation of the ICU admission rate after NIV in postoperative management of obese patients

Time frame: 72 hours

Blood oxygen saturation (SaPo2)

the evaluation of the oximetry values of obese patients after postoperative NIV adoption

Time frame: 12 hours