Patients with chronic stroke (\>6 months after stroke) having unilateral upper limb hemiparesis will be recruited. Patients will maintain their usual inpatient rehabilitation including occupational therapy. At baseline (T0) and after 2weeks of enrollment (T1), Fugl-Meyer assessment (FMA) will be assessed at each time. And patients with the changes of FMA between T0 and T1 less than 3 points will be finally recruited. The enrolled patients will receive additional 30-min cathodal transcranial direct current stimulation (tDCS) over the contralesional motor cortex for 10 consecutive weekdays, with maintaining their usual conventional rehabilitation. At T1 and immediately after 10-seessions of tDCS (T2) and 1 month after completing 10-tDCS session (T3), FMA, Actional Research Arm Test (ARAT), Box and Block Test (BBT) and electroencephalography (EEG) were measured.
Study Type
OBSERVATIONAL
Enrollment
100
Cathodal tDCS will be applied to the contralesional motor cortex with 2mA intesntisy for 30 mins/day. Total 10 sessions will be applied.
Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, South Korea
RECRUITINGRusk Rehabilitation Hospital
Seongnam-si, Please Select, South Korea
RECRUITINGChanges in Fugl-Meyer Assesment Score 1
Time frame: Between T1 (before tDCS) and T2 (immediately after completing 10 sessions of tDCS)
Changes in Fugl-Meyer Assesment Score 2
Time frame: Between T2 (immediately after completing 10 sessions of tDCS) and T3 (1 month after completing 10 sessions of tDCS)
Changes in Action Research Arm Test Score 1
Time frame: Between T1 (before tDCS) and T2 (immediately after completing 10 sessions of tDCS)
Changes in Action Research Arm Test Score 2
Time frame: Between T2 (immediately after completing 10 sessions of tDCS) and T3 (1 month after completing 10 sessions of tDCS)
Changes in Box and Block Test Score 1
Time frame: Between T1 (before tDCS) and T2 (immediately after completing 10 sessions of tDCS)
Changes in Box and Block Test Score 2
Time frame: Between T2 (immediately after completing 10 sessions of tDCS) and T3 (1 month after completing 10 sessions of tDCS)
Changes in EEG index1
Various kinds of EEG indexe.g., network indexes, event-related dysynchronization, mu suppression) will be surveyed.
Time frame: Between T1 (before tDCS) and T2 (immediately after completing 10 sessions of tDCS)
Changes in EEG index 2
Various kinds of EEG indexe.g., network indexes, event-related dysynchronization, mu suppression) will be surveyed.
Time frame: Between T2 (immediately after completing 10 sessions of tDCS) and T3 (1 month after completing 10 sessions of tDCS)
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