This study aims at evaluating, in chronic kidney disease patients on dialysis, the effect of acute per- or pre-dialytic physical exercise on regional myocardial function and myocardial stunning, blood viscosity, arterial stiffness, variability of sinus rhythm, dialysis efficacy, inflammation, mineral and bone disorders, myokines and cardiac remodeling markers.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
OTHER
Masking
NONE
Enrollment
32
Hemodialysis control condition
Patients will pedal for 30 minutes using a ergometer directly attached to the dialysis bed. The exercise will be performed 60 minutes before connection to hemodialysis.
Patients will pedal for 30 minutes using a ergometer directly attached to the dialysis bed. The exercise will start 30 minutes after the start of dialysis.
Lapeyronie Hospital clinical trials Department
Montpellier, Hérault, France
NOT_YET_RECRUITINGAIDER Santé
Montpellier, France
RECRUITINGChange in regional myocardial function and myocardial stunning
Time frame: Weekly over a period of 3 weeks
Change in blood viscosity
Time frame: Weekly over a period of 3 weeks
Change in arterial stiffness
Time frame: Weekly over a period of 3 weeks
Change in sinus rhythm
Time frame: Weekly over a period of 3 weeks
Change in dialysis efficacy
Time frame: Weekly over a period of 3 weeks
Change in inflammatory markers
Time frame: Weekly over a period of 3 weeks
Change in mineral and bone metabolism markers
Time frame: Weekly over a period of 3 weeks
Change in myokines
Time frame: Weekly over a period of 3 weeks
Change in cardiac remodeling markers
Time frame: Weekly over a period of 3 weeks
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