Narrow Band Imaging in Diagnosis of Colorectal Polyps

Prince of Songkla University118 enrolled

Overview

Optical diagnosis of colorectal polyps is a promising tool to avoid risks of unnecessary polypectomies and to save costs of tissue pathology. NICE (NBI International Colorectal Endoscopic) and WASP (Workgroup on Serrated Polyps and Polyposis) classification were developed for diagnosis of adenomatous and sessile serrated polyps, respectively.

Near-focus (NF) narrow-band imaging (NBI) is an image-magnifying technology which enables optical magnification of up to 65x in near focus (NF) compared with 52x in normal standard focus (SF) with the simple push of a button of the endoscope to be interchangeable between NF and SF. There were few studies comparing diagnostic accuracy between NF and SF in the diagnosis of colorectal polyps. So, our aim of the current study is to compare accuracy of NF NBI compared with SF NBI in the optical diagnosis of neoplastic and non-neoplastic polyp and the accuracy of NF NBI versus SF NBI in distinguishing serrated adenoma from hyperplastic polyp in sessile lesions using histologic evaluation as the gold standard.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

118

Conditions

Colorectal Polyp Colorectal Neoplasms

Interventions

Near Focus NBIDIAGNOSTIC_TEST

Colonoscopy with near focus narrowing band imaging technology . Optical specifications include a 2 mm near field focal depth. Optical diagnosis of polyps were according to NICE and WASP, respectively.

Standard Focus NBIDIAGNOSTIC_TEST

Colonoscopy with narrow band imaging technology.Optical diagnosis of polyps were according to NICE and WASP, respectively.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients who were scheduled for colonoscopy at NKC institute Exclusion Criteria: * Inflammatory bowel disease * Polyposis syndrome * Colorectal cancer * Active gastrointestinal bleeding * Pregnant woman * Inadequate bowel preparation * Contraindication for polyps removal

Locations (1)

Prince Songkla University

Hat Yai, Changwat Songkhla, Thailand

Outcomes

Primary Outcomes

Rate of accurate polyp histology predictions by the Endoscopists in the two groups.

Measure of the percentage of accurate predictions by the endoscopists in the differentiation of neoplastic from non neoplastic colorectal lesions, using the high definition NBI colonoscopy with and without near focus features