Effects of Different Fresh Gas Flows on Carboxyhemoglobin Levels

Zonguldak Bulent Ecevit University64 enrolled

Overview

To observe the effect of different fresh flows (1 L / min and 4 L / min) on the carboxyhemoglobin level non-invasively and continuous measurement and to determine the contribution of smoking to the intraoperative carbon monoxide accumulation.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Fresh Flow Carboxyhemoglobinemia

Interventions

Radical-7 Pulse CO-OximeterDEVICE

COHb measurement monitoring from finger pulp with a non-invasive measurement device called Masimo Radical-7 Pulse co-oximeter (Masimo Corporation, Irvine, USA)

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * ASA I-II * Undergo 2-4 hours of elective surgery Exclusion Criteria: * Cardiovascular disease * diabetes mellitus * kidney, liver failure * chronic obstructive pulmonary disease * patients with opioid sensitivity * morbidly obese * personal or family history of malignant hyperthermia * history of prolonged recovery from anesthesia * alcohol addicted * pregnant and breastfeeding women patients allergic to study drugs

Locations (1)

Zonguldak Bülent Ecevit University Medicine Faculty

Zonguldak, Kozlu, Turkey (Türkiye)

Outcomes

Primary Outcomes

effects of different fresh gas flows on carboxyhemoglobin levels

To observe the effect of different fresh flows (1 L / min and 4 L / min) on the carboxyhemoglobin level by non-invasive and continuous measurement.

Time frame: during surgery

Secondary Outcomes

effects of smoking on carbon monoxide accumulation.

to determine the contribution of smoking to intraoperative carbon monoxide accumulation.

Time frame: during surgery

Data from ClinicalTrials.gov

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