Positron Emission Tomography (PET) Imaging of Participants With Confirmed Prostate Cancer Using 64Cu-SAR-bisPSMA (PROPELLER)

Inclusion Criteria: * Signed informed consent; * ≥18 years of age; * Life expectancy \>3 months; * Confirmation of Prostate Cancer by histopathology and planned radical prostatectomy; * Have ≥1 of the following intermediate- to high-risk features: 1. PSA level greater than or equal to 10.0 ng/ml within 12 weeks prior to enrolment; 2. International Society of Urological Pathology (ISUP) Grade Group 3 (i.e. Gleason score of 7 (4+3) or above; 3. Clinical stage greater than or equal to T2b; * Participants must have adequate renal function; * Sexually active participants who have female partners of childbearing potential: Partner and/or participant must agree to use an acceptable form of contraception. Further participants must refrain from donating sperm; * A 68Ga-PSMA-11 PET/CT scan performed within 5 weeks, but not closer than 6 hours prior to the administration of 64Cu-SAR-bisPSMA. Exclusion Criteria: * Prior prostatectomy or any other treatment for Prostate Cancer, including Androgen Deprivation Therapy and radiation therapy; * Previous treatment with PSMA-targeted therapy within 3 months prior to enrolment, and administration of other investigational agents within 4 weeks prior to entering the study (except 68Ga-PSMA-11); * Known hypersensitivity to the components of 64Cu-SAR-bisPSMA; * Diagnosed with other malignancies that are expected to alter life expectancy or may interfere with disease assessment. However, participants with a prior history of malignancy that has been adequately treated and who have been disease free for more than 3 years are eligible, as are participants with adequately treated non-melanoma skin cancer, superficial bladder cancer; * Any serious medical condition which the Investigator feels may interfere with the procedures or evaluations of the study; * Patients unwilling or unable to comply with protocol or with a history of noncompliance or inability to grant informed consent.